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Tell your doctor about all your current medicines, especially riociguat (Adempas) and nitrates. General information about the safe and effective use of VIAGRA. Sildenafil should not be used with any other medicine or device that causes erections. If you will be taking this medicine for pulmonary arterial hypertension, your doctor will want to check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.

In studies with healthy volunteers of single doses up to 800 mg, adverse reactions were similar to those seen at lower doses but incidence rates and severities were increased. Analysis of the safety database from controlled clinical trials showed no apparent difference in adverse reactions in patients taking VIAGRA with and without anti-hypertensive medication. This analysis was performed retrospectively, and was not powered to detect any pre-specified difference in adverse reactions. Counseling of patients about the protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), may be considered. However, there are no controlled clinical data on the safety or efficacy of VIAGRA in patients with sickle cell or related anemias. For example, a study conducted at McMaster University examined the effect of sildenafil on erectile function in men with diabetes mellitus.

If use of a nitrate-containing medication is considered medically necessary, you must wait 48 hours after the last dose of sildenafil before taking a nitrate, and only under close medical supervision. Other medical conditions you have can also affect your Viagra dosage. Specifically, you may have a lower starting dosage than usual if you’re over age 65. For example, a 30-year-old might start at a dose of 50 milligrams (mg), while a 70-year-old might have a starting dose of 25 mg.

Do not take any more doses of sildenafil or similar medications such as tadalafil (Cialis) or vardenafil (Levitra) until you talk to your doctor. For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. Sildenafil causes mild and transient decreases in blood pressure which, in the majority of cases, do not translate into clinical effects. The mean maximum decreases in supine systolic blood pressure following 100 mg oral dosing of sildenafil was 8.4 mmHg. The corresponding change in supine diastolic blood pressure was 5.5 mmHg.

If you have any questions or concerns about your health, please speak to your doctor. You have probably heard wonders about this little blue pill, but is it really that effective? In this article, we aim to answer some of your questions surrounding Viagra, such as how long it lasts, and what dosage you should start with. We also explain the factors affecting Viagra’s overall effectiveness, and include tips to increase its efficacy. Please read the package insert or consult pharmacist for possible side effects of this medicine.

Thanks to generous benefactors, your gift today can have 5X the impact to advance AI innovation at Mayo Clinic. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. The medicine will come with a plastic syringe or spoon to help you take the right amount. If you do not have a plastic syringe or spoon, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not measure the right amount. Swallow tablets whole with a drink of water or juice (but not grapefruit juice).

How effective and long Viagra lasts in your system also depends on your pre-existing health conditions. To err on the safe side, we recommend that you consult a medical professional before consuming Viagra. Viagra generally starts working within 30 to 60 minutes after consumption. To determine what initial dosage is best for you, we recommend seeking professional advice from trained doctors, which we offer here at Noah.

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